Tmem45a gene

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August undefined, 2024

WebApr 1, 2014 · In vivo, TMEM45A mRNA and protein are mostly found in the granular layer of the epidermis. TMEM45A expression is linked to keratinization, as accumulation of the protein is detected in native and reconstructed epidermis as well as in thymic Hassal bodies, but not in non-keratinized stratified epithelia. WebMicroarray gene expression profiling and quantitative RT-PCR revealed that upregulation of TMEM45A correlated with taxol resistance in MDA-MD-231 cells and etoposide resistance …

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WebJul 14, 2015 · We found 10 significantly deregulated genes (8 down- and 2 up-regulated) which were represented by gene transcripts belonging to TMEM gene family, with highest down-regulation of TMEM213 (effect size = −11.7) and highest up-regulation of TMEM45A (effect size = 2.6) . TMEMs are a group of ca. 310 different proteins (with ca. 440 … http://www.informatics.jax.org/marker/mgi:1913122 roof repair in fayetteville

56277 - Gene ResultTmem45a transmembrane protein 45a

WebApr 1, 2014 · In vivo, TMEM45A mRNA and protein are mostly found in the granular layer of the epidermis. TMEM45A expression is linked to keratinization, as accumulation of the … WebDec 1, 2024 · TMEM45A is a transmembrane protein involved in tumor progression and cancer resistance to chemotherapeutic agents in hypoxic condition. It is correlated to a low breast cancer patient overall... WebTMEM45A shRNA suppressed the proliferation of SiHa and HeLa cells, arrested cells at the S phase, and promoted cell apoptosis. TMEM45A shRNA inhibited the epithelial … roof repair in dover

Characterization of the role of TMEM45A in cancer cell

Gene targeting of Tmem45a by homologous recombination in …

WebMar 21, 2024 · TMEM45A (Transmembrane Protein 45A) is a Protein Coding gene. Diseases associated with TMEM45A include Pollen Allergy and Fanconi Anemia, Complementation Group A . An important paralog of this gene is TMEM45B. Additional gene information for … SPP1 (Secreted Phosphoprotein 1) is a Protein Coding gene. Diseases … IGFBP5 (Insulin Like Growth Factor Binding Protein 5) is a Protein Coding gene. … http://www.informatics.jax.org/marker/mgi:1913122 roof repair in davie flWebTMEM45A has 5,568 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, … roof repair in chesterfield

"WebSep 8, 2024 · A study links the rare corneal disorder and variants in the TMEM45A gene. A case series found that isolated congenital keratoglobus is likely an inherited, autosomal recessive disorder. These findings were published in JAMA Ophthalmology. " - Tmem45a gene

Tmem45a gene

Keratoglobus Associated With Gene Variation, Study Shows

WebShowing subcellular location of TMEM45A (DERP7, FLJ10134). We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again. TMEM45A. SECTIONS. ... WebTMEM45A. The antibodies are designated mAB for monoclonal and pAb for polyclonal. The release of the Human Protein Atlas in which the antibody was first published. All assays through which the antibody has been validated. Assays&annotation provide a detailed description of the different assays. The pie-charts indicate degree of validation.

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WebFeb 1, 2024 · Interestingly, TMEM16A gene is amplified in different types of cancer: in 30% of esophagus cancers, in 25% of HNSCC and in 15% of breast or lung cancers. The activity of this channel modifies the MAPK pathway, which regulates cell proliferation. ... TMEM45A is a protein localized in the membrane of the Golgi apparatus which is highly expressed ... WebThis website you visit will use cookies in order to improve your user experience by enabling that website to ‘remember’ you. Should you continue navigating we will consider that you accept their use.

WebJan 19, 2016 · TMEM45A gene encodes an initially uncharacterized predicted transmembrane protein. We previously showed that this gene is highly expressed in … WebTMEM45A. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC.

WebTMEM45A has 5,568 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 61 datasets. WebDec 4, 2024 · TMEM45A was upregulated in patients diagnosed for head and neck or renal cancer. Then, the implication of this protein in cisplatin sensitivity was explored in SQD9 and RCC4 + pVHL cells. TMEM45A inactivation decreased cell proliferation and modulated cell responses to cisplatin. Indeed, TMEM45A inactivation increased the sensitivity of SQD9 ...

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WebNational Center for Biotechnology Information roof repair in columbia moWebAnti-TMEM45A antibody [EPR9783(B)] - BSA and Azide free (ab249381) ... The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Two transcript ... roof repair in fort myersWebtmem45a ID ZDB-GENE-050522-34 Name transmembrane protein 45a Symbol tmem45a Nomenclature History Previous Names. im:6904866; zgc:110647; Type … roof repair in garland