Meg3 gene function

Author: msde

August undefined, 2024

WebAlthough thousands of long noncoding RNAs (lncRNAs) have been identified in porcine growth and development, the regulation mechanisms of functional lncRNAs have not been well explored. In this study, using 5′- and 3′-rapid amplification of cDNA ends (RACE) assays, we obtained two different variants of lncRNA maternally expressed gene 3 … WebAlthough thousands of long noncoding RNAs (lncRNAs) have been identified in porcine growth and development, the regulation mechanisms of functional lncRNAs have not …

Activation of p53 by MEG3 Non-coding RNA*

Web24 aug. 2007 · MEG3 is a maternally expressed imprinted gene suggested to function as a non-coding RNA. Our previous studies suggest that MEG3 has a function of tumor … Web14 feb. 2024 · Meg3 has been shown to play an important role in the regulation of cellular proliferation and functions as a tumor suppressor in numerous tissues. Meg3 is highly … charcoal toothpaste manufacturers 33027

The IG-DMR and the MEG3-DMR at Human Chromosome …

WebAbout. • An experienced scientist with 17+ years research experience in genetics, cellular and molecular biology, tissue culture, CRISPR-Cas9 gene knock out, siRNA, mRNA, epigenetics, T cells ... Web2 apr. 2012 · MEG3 induces accumulation of p53 (TP53) protein, stimulates transcription from a p53-dependent promoter, and selectively regulates p53 target gene expression. … Web29 mrt. 2024 · MEG3 executed its functions via EZH2 to regulate the downstream target gene LATS2. MEG3 inhibits Hh-mediated EMT process in liver fibrosis via SMO … harrington and king perforated metal

The association of MEG3 lncRNA with nuclear speckles in living cells

Web1 nov. 2003 · The MEG3 cDNA isoform MEG3a (see Fig. 1A for sequence), obtained from the library screening, was cloned into pCI-neo (Promega, Madison, WI) via the 5′-EcorRI … Web19 okt. 2014 · We used gene co-expression network analysis to functionally annotate long noncoding RNAs (lncRNAs) and identify their potential cancer associations. The integrated microarray data set from our prev... Co-expression Network Analysis of Human lncRNAs and Cancer Genes - Steven B. Cogill, Liangjiang Wang, 2014 Skip to main content charcoal toothpaste for transparent teethWebA maternally expressed gene 3 (MEG3) gene transcripts a 1.6 kb lncRNA whose act as an antitumor component in different cancer cells, such as breast, liver, glioma, colorectal, cervical, gastric, lung, ovarian and osteosarcoma cancer cells. The present review highlights biological function of MEG3 to repress tumor through regulating the charcoal toothpaste in india

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Meg3 gene function

MEG3 long noncoding RNA regulates the TGF-β pathway …

Web8 aug. 2015 · Long noncoding RNAs (lncRNAs) have recently emerged as important regulators in governing fundamental biological processes, and many of which are likely to have functional roles in tumorigenesis. Maternally expressed gene 3 (MEG3) gene encodes a lncRNA whose expression is lost in an expanding list of primary human … Web8 okt. 2024 · The maternally expressed gene 3 ( MEG3) was the first lncRNA proposed to have a tumor suppressor function ( 10, 11 ). Using cDNA-representational difference analysis, MEG3 expression was not detected in either pituitary tumors, when compared to normal human pituitary tissue, nor in several human cancer cell lines ( 10 ).

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WebMEG3 HGNC:14575 55384 (Entrez Gene) 605636 MEG3 (Alliance of Genome Resources) Chr14 q32.2: Chr14:100826108-100861026 (+) GRCh38.p7: NM_018514 : mouse: Meg3: MGI:1202886 17263 (Entrez Gene) Gene Tree Meg3 (Alliance of Genome Resources) Chr12 60.25 cM Web15 feb. 2024 · growth and development, the regulation mechanisms of functional lncRNAs have not been well explored. In this study, using 50- and 30-rapid ampliﬁcation of cDNA ends (RACE) assays, we obtained two di erent variants of lncRNA maternally expressed gene 3 (MEG3), namely, MEG3

Web1 feb. 2024 · The hypothesis that exosomal MEG3 in urine can be used as a novel diagnostic biomarker for Hunner‐type interstitial cystitis is verified. Toll‐like receptor‐7 (TLR7) is functionally involved in the pathogenesis of Hunner‐type interstitial cystitis (HIC). In addition, maternally expressed gene 3 (MEG3) is implicated in many urethral diseases. … WebDown-regulation of lncRNA MEG3 promotes hypoxia-induced human pulmonary artery smooth muscle cell proliferation and migration via repressing PTEN by sponging miR-21. Author links open overlay panel Boqian Zhu a 1, Yaoyao Gong b 1, Gaoliang Yan a, Dong Wang a, Yong Qiao a, Qingjie Wang c, Bo Liu a, Jiantong Hou a, Ruifeng Li a, …

WebMaternally expressed gene 3 (MEG3), located on human chromosome 14q32, is a maternally expressed imprinted gene expressed in many normal tissues. 12 It has been … WebLncRNA MEG3 promotes the sensitivity of bortezomib by inhibiting autophagy in multiple myeloma. Long non-coding RNA MEG3 and its genetic variant rs941576 are associated …

WebThe MEG3 gene encodes a noncoding RNA of approximately 1700 nucleotides. There are 12 different MEG3 gene transcripts, generated by alternative splicing. They contain …

Web1 jun. 2010 · This gene is highly expressed in the normal human brain and pituitary, including gonadotroph cells from which clinically nonfunctioning tumors are mainly … charcoal toothpaste general discountWeb24 jul. 2015 · Here we show that MEG3 and EZH2 share common target genes, including the TGF-β pathway genes. Genome-wide mapping of MEG3 binding sites reveals that … charcoal toothpaste health benefitsWeb16 jun. 2024 · of the intergenic regions [47]. MEG3 was identiﬁed to partially associate with the nuclear speckles [37] and since lncRNAs often localize to their site of action, this localization could shed light on the connections of MEG3 to the gene expression pathway. In this study, we examined the dynamics of MEG3 lncRNA in the nucleus of living cells. charcoal toothpaste japan