WebPaclitaxel is a high-alert IV oncology medication that causes hypersensitivity reactions (HSRs) in 10%–40% of infusions, predominantly during the first or second … WebHypersensitivity reactions to paclitaxel occur in 3-30% of treated patients and most frequently manifest as dyspnea, bronchospasm, urticaria, hypotension, and erythematous rashes . To our knowledge, the radiologic findings of paclitaxel-induced hypersensitivity pneumonitis have not previously been described in the radiology literature.
Hypersensitivity Reactions Associated with Platinum …
WebHowever, paclitaxel and docetaxel, which are the most commonly used taxanes, elicit immediate hypersensitivity reactions (HSRs) in 5% to 10% of patients. Almost all … Web2 aug. 2024 · Paclitaxel has also been isolated from hazelnuts , and hypersensitivity reactions to both paclitaxel and hazelnut ingestion have been described . Other … csx railroad traffic data
Hypersensitivity Reactions: Practice Recommendations for …
Web29 jan. 2015 · Incidence of Paclitaxel-Associated Hypersensitivity Reaction (P-HSRs) and severe P-HSRs (Safety endpoint) [ Time Frame: 3 Hours after starting paclitaxel … Web6 aug. 2024 · In the late 1980s, more than a dozen phase I studies analyzed the efficacy of paclitaxel as a single agent. 4-9 Without premedication, hypersensitivity reactions (HSRs) occurred in 25%-30% of patients in these studies and clinical development of paclitaxel was consequently delayed. 3,10 In subsequent trials, 11-16 patients were premedicated with … Web4 jun. 2024 · Paclitaxel (PTX) injection (i.e., Taxol) has been used as an effective chemotherapeutic treatment for various cancers. However, the current Taxol formulation contains Cremophor EL, which causes hypersensitivity reactions during intravenous administration and precipitation by aqueous dilution. This communication reports the … csx pipeline specs